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Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma

Expression of the apoptosis-promoting Fas gene is frequently reduced or lost during the development of colorectal carcinoma. However, loss of heterozygosity at the Fas locus or Fas gene rearrangements do not account for the loss of expression of Fas, raising the possibility that methylation of the F...

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Detalles Bibliográficos
Autores principales: Butler, L M, Dobrovic, A, Bianco, T, Cowled, P A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363214/
https://www.ncbi.nlm.nih.gov/pubmed/10638979
http://dx.doi.org/10.1054/bjoc.1999.0889