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Development and characterization of a tamoxifen-resistant breast carcinoma xenograft

A human tamoxifen-resistant mammary carcinoma, MaCa 3366/TAM, originating from a sensitive parental xenograft 3366 was successfully established by treatment of tumour-bearing nude mice with 1–50 mg kg(−1)tamoxifen for 3 years during routine passaging. Both tumours did not differ significantly in OR-...

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Detalles Bibliográficos
Autores principales: Naundorf, H, Becker, M, Lykkesfeldt, A E, Elbe, B, Neumann, C, Büttner, B, Fichtner, I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363223/
https://www.ncbi.nlm.nih.gov/pubmed/10839300
http://dx.doi.org/10.1054/bjoc.2000.1156