Cargando…

Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis

We have previously shown that the androgen-independent prostate cancer cells DU145, despite expressing Fas and FasL, were resistant to anti-Fas-induced apoptosis, and that this resistance could be overcome by pretreating the cells with sublethal doses of camptothecin. Here, we provide evidence that...

Descripción completa

Detalles Bibliográficos
Autores principales: Costa-Pereira, A P, McKenna, S L, Cotter, T G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363235/
https://www.ncbi.nlm.nih.gov/pubmed/10839298
http://dx.doi.org/10.1054/bjoc.2000.1149