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Induction of apoptosis and activation of the caspase cascade by anti-EGF receptor monoclonal antibodies in DiFi human colon cancer cells do not involve the c- jun N-terminal kinase activity

We previously reported that exposure of DiFi human colon cancer cells to the anti-epidermal growth factor (EGF) receptor monoclonal antibody (mAb) 225 resulted in apoptosis, but the mechanisms remain to be elucidated. In the present study, we investigated the effects of a panel of four anti-EGF rece...

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Detalles Bibliográficos
Autores principales: Liu, B, Fang, M, Schmidt, M, Lu, Y, Mendelsohn, J, Fan, Z
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363248/
https://www.ncbi.nlm.nih.gov/pubmed/10864208
http://dx.doi.org/10.1054/bjoc.2000.1201