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Suppressed tumorigenicity of human endometrial cancer cells by the restored expression of the DCC gene

To obtain functional evidence for DCC as a tumour suppressor associated with endometrial cancer, the human DCC cDNA encoding a complete open reading frame (ORF) was transfected into highly tumorigenic human endometrial carcinoma cells, HHUA and Ishikawa in which DCC expression was completely deleted...

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Detalles Bibliográficos
Autores principales: Kato, H, Zhou, Y, Asanoma, K, Kondo, H, Yoshikawa, Y, Watanabe, K, Matsuda, T, Wake, N, Barrett, J C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363268/
https://www.ncbi.nlm.nih.gov/pubmed/10646905
http://dx.doi.org/10.1054/bjoc.1999.0943