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Detection of codon 12 K- ras mutations in non-neoplastic mucosa from bronchial carina in patients with lung adenocarcinomas

K- ras activation by point mutation in codon 12 has been reported in lung adenocarcinomas in various models of experimental lung tumours induced by chemical carcinogens. The hypothesis of the presence of cells containing K- ras mutation in non neoplastic bronchial carina, the main site of impaction...

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Detalles Bibliográficos
Autores principales: Urban, T, Ricci, S, Danel, C, Antoine, M, Kambouchner, M, Godard, V, Lacave, R, Bernaudin, J-F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363273/
https://www.ncbi.nlm.nih.gov/pubmed/10646897
http://dx.doi.org/10.1054/bjoc.1999.0935