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Search for NTRK1 proto-oncogene rearrangements in human thyroid tumours originated after therapeutic radiation
Rearrangements of NTRK1 proto-oncogene were detected in ‘spontaneous’ papillary thyroid carcinomas with a frequency varying from 5 to 25% in different studies. These rearrangements result in the formation of chimaeric genes composed of the tyrosine kinase domain of NTRK1 fused to 5′ sequences of dif...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363282/ https://www.ncbi.nlm.nih.gov/pubmed/10646882 http://dx.doi.org/10.1054/bjoc.1999.0920 |