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BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma

The expression of the BCL-2 family proteins, BCL-2, BAX, BCL(XL)and BAK have been determined in a panel of 12 human ovarian carcinoma cell lines encompassing a wide range in sensitivity to cisplatin. Whereas BAX, BCL(XL)and BAK levels did not correlate with sensitivity, there was a statistically sig...

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Detalles Bibliográficos
Autores principales: Beale, P J, Rogers, P, Boxall, F, Sharp, S Y, Kelland, L R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363292/
https://www.ncbi.nlm.nih.gov/pubmed/10646901
http://dx.doi.org/10.1054/bjoc.1999.0939