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Hypermethylation of ribosomal DNA in human breast carcinoma

We examined the methylation status of the transcribed domain of ribosomal DNA (rDNA) in 58 patients with breast cancer. The mean percent of methylation was significantly higher in breast tumours than that of normal control samples (P< 0.0001). This increased rDNA methylation was associated with o...

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Detalles Bibliográficos
Autores principales: Yan, P S, Rodriguez, F J, Laux, D E, Perry, M R, Standiford, S B, Huang, T H-M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363317/
https://www.ncbi.nlm.nih.gov/pubmed/10682657
http://dx.doi.org/10.1054/bjoc.1999.0955