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p53-dependent G2 arrest associated with a decrease in cyclins A2 and B1 levels in a human carcinoma cell line

In vivo transfer of wild-type (wt) p53 gene via a recombinant adenovirus has been proposed to induce apoptosis and increase radiosensitivity in several human carcinoma models. In the context of combining p53 gene transfer and irradiation, we investigated the consequences of adenoviral-mediated wtp53...

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Detalles Bibliográficos
Autores principales: Badie, C, Bourhis, J, Sobczak-Thépot, J, Haddada, H, Chiron, M, Janicot, M, Janot, F, Tursz, T, Vassal, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363318/
https://www.ncbi.nlm.nih.gov/pubmed/10682678
http://dx.doi.org/10.1054/bjoc.1999.0976