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Interaction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulin

The processes by which ErbB-3, an inactive tyrosine kinase, exerts its biological effects are poorly understood. Using the yeast two-hybrid system, we have isolated an ErbB-3 binding protein (Ebp1) that interacts with the juxtamembrane domain of ErbB-3. This protein is identical to that predicted to...

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Detalles Bibliográficos
Autores principales: Yoo, J-Y, Wang, X W, Rishi, A K, Lessor, T, Xia, X-M, Gustafson, T A, Hamburger, A W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363329/
https://www.ncbi.nlm.nih.gov/pubmed/10682683
http://dx.doi.org/10.1054/bjoc.1999.0981