Mutational status of K- ras and TP53 genes in primary sarcomas of the heart

We investigated three patients with cardiac angiosarcomas and two with cardiac rhabdomyosarcomas, all for mutations at exons 5, 6, 7 and 8 of the p53 gene and at exon 1 of K- ras. No point mutations were observed in the p53 gene in any of the five cases; however, at exon 1 of K- ras, three patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Garcia, J M, Gonzalez, R, Silva, J M, Dominguez, G, Vegazo, I S, Gamallo, C, Provencio, M, España, P, Bonilla, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363343/
https://www.ncbi.nlm.nih.gov/pubmed/10735503
http://dx.doi.org/10.1054/bjoc.1999.1060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363343/
https://www.ncbi.nlm.nih.gov/pubmed/10735503
http://dx.doi.org/10.1054/bjoc.1999.1060

Ejemplares similares