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Mutational status of K- ras and TP53 genes in primary sarcomas of the heart
We investigated three patients with cardiac angiosarcomas and two with cardiac rhabdomyosarcomas, all for mutations at exons 5, 6, 7 and 8 of the p53 gene and at exon 1 of K- ras. No point mutations were observed in the p53 gene in any of the five cases; however, at exon 1 of K- ras, three patients...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2000
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363343/ https://www.ncbi.nlm.nih.gov/pubmed/10735503 http://dx.doi.org/10.1054/bjoc.1999.1060 |