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Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features

The FHIT gene is located at a chromosomal site (3p14.2) which is commonly affected by translocations and deletions in human neoplasia. Although FHIT alterations at the DNA and RNA level are frequent in many types of tumours, the biological and clinical significance of these changes is not clear. In...

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Detalles Bibliográficos
Autores principales: Geradts, J, Fong, K M, Zimmerman, P V, Minna, J D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363352/
https://www.ncbi.nlm.nih.gov/pubmed/10735505
http://dx.doi.org/10.1054/bjoc.1999.1062