Enhancement of the anti-tumour effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine

The ability of the bioreductive drugs AQ4N and tirapazamine to enhance the anti-tumour effect of cyclophosphamide was assessed in three murine tumour models. In male BDF mice implanted with the T50/80 mammary carcinoma, AQ4N (50–150 mg kg(−1)) in combination with cyclophosphamide (100 mg kg(−1)) pro...

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Detalles Bibliográficos
Autores principales: Friery, O P, Gallagher, R, Murray, M M, Hughes, C M, Galligan, E S, McIntyre, I A, Patterson, L H, Hirst, D G, McKeown, S R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363362/
https://www.ncbi.nlm.nih.gov/pubmed/10780528
http://dx.doi.org/10.1054/bjoc.1999.1132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363362/
https://www.ncbi.nlm.nih.gov/pubmed/10780528
http://dx.doi.org/10.1054/bjoc.1999.1132

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