Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) and paclitaxel

A clinical study of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) in combination with paclitaxel was performed. The aims were to optimize the schedule of administration and determine any pharmacokinetic (PK) interactions between the two drugs. In vitro combination studies were performed to assist...

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Detalles Bibliográficos
Autores principales: Hughes, A N, Griffin, M J, Newell, D R, Calvert, A H, Johnston, A, Kerr, B, Lee, C, Liang, B, Boddy, A V
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363406/
https://www.ncbi.nlm.nih.gov/pubmed/10789718
http://dx.doi.org/10.1054/bjoc.2000.1172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363406/
https://www.ncbi.nlm.nih.gov/pubmed/10789718
http://dx.doi.org/10.1054/bjoc.2000.1172

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