Cargando…

Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases

F 11782 is a novel inhibitor of topoisomerases I and II, with an original mechanism of action (Perrin et al, 2000). This study, aimed to define its anticancer efficacy against a series of murine and human tumour models, has provided evidence of major antitumour activity for F 11782. This was demonst...

Descripción completa

Detalles Bibliográficos
Autores principales: Kruczynski, A, Etiévant, C, Perrin, D, Imbert, T, Colpaert, F, Hill, B T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363411/
https://www.ncbi.nlm.nih.gov/pubmed/11076662
http://dx.doi.org/10.1054/bjoc.2000.1428