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Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases
F 11782 is a novel inhibitor of topoisomerases I and II, with an original mechanism of action (Perrin et al, 2000). This study, aimed to define its anticancer efficacy against a series of murine and human tumour models, has provided evidence of major antitumour activity for F 11782. This was demonst...
Autores principales: | Kruczynski, A, Etiévant, C, Perrin, D, Imbert, T, Colpaert, F, Hill, B T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363411/ https://www.ncbi.nlm.nih.gov/pubmed/11076662 http://dx.doi.org/10.1054/bjoc.2000.1428 |
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