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Exploiting changes in the tumour microenvironment with sequential cytokine and matrix metalloprotease inhibitor treatment in a murine breast cancer model

The study of treatment-induced changes in the tumour microenvironment might lead to effective combinations of biological therapy. IL-12 induced tumour regression and cure of an experimental murine breast cancer, HTH-K, but only after long-term treatment that was associated with chronic toxicity. Dur...

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Detalles Bibliográficos
Autores principales: Scott, K A, Holdsworth, H, Balkwill, F R, Dias, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363423/
https://www.ncbi.nlm.nih.gov/pubmed/11076665
http://dx.doi.org/10.1054/bjoc.2000.1487