Prolonged and enhanced suppression of thymidylate synthase by weekly 24-h infusion of high-dose 5-fluorouracil

We have recently demonstrated that HDFL (high-dose 5-FU 2600 mg m–2 week–1 and leucovorin 500 mg m–2 week–1, weekly 24-h infusion) is highly active in the treatment of gastric cancer. To further clarify the possible mechanism underlying the improved activity of HDFL compared with conventional 5-FU r...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeh, K-H, Yeh, S-H, Hsu, C-H, Wang, T-M, Ma, I-F, Cheng, A-L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363429/
https://www.ncbi.nlm.nih.gov/pubmed/11076661
http://dx.doi.org/10.1054/bjoc.2000.1456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363429/
https://www.ncbi.nlm.nih.gov/pubmed/11076661
http://dx.doi.org/10.1054/bjoc.2000.1456

Ejemplares similares