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Characterization of DNA-strand breakage induced in V79 cells by F 11782, a catalytic inhibitor of topoisomerases

DNA damage induced in V79 cells by F 11782, or 2″,3″-bis pentafluorophenoxyacetyl-4′,′-ethylidene-β-D glucoside of 4′-phosphate-′-demethylepipodophyllotoxin 2N-methyl glucamine salt, a novel dual catalytic inhibitor of topoisomerases I and II, was investigated using both alkaline and neutral version...

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Detalles Bibliográficos
Autores principales: Barret, J-M, Hill, B T, Olive, P L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363439/
https://www.ncbi.nlm.nih.gov/pubmed/11104575
http://dx.doi.org/10.1054/bjoc.2000.1514