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Anti-CD7 antibody and immunotoxin treatment of human CD7(+)T-cell leukaemia is significantly less effective in NOD/LtSz-scid mice than in CB.17 scid mice

Groups of 8 to ten SCID (CB.17 scid/scid) or NOD/SCID (NOD/LtSz- scid/scid) mice were injected i.v. with two million human HSB-2 T-ALL cells on day 1 (SCID-HSB-2 and NOD/SCID-HSB-2 mice) and treated later with 3 i.v. 10 μg doses of the anti-CD7 antibody HB2 on days 7, 9 and 11 or with a single 10 μg...

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Dettagli Bibliografici
Autori principali: Flavell, D J, Warnes, S L, Noss, A L, Flavell, S U
Natura: testo
Lingua:English
Pubblicazione: Nature Publishing Group 2000
Soggetti:
Accesso online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363443/
https://www.ncbi.nlm.nih.gov/pubmed/11104577
http://dx.doi.org/10.1054/bjoc.2000.1565