Cargando…

Anti-CD7 antibody and immunotoxin treatment of human CD7(+)T-cell leukaemia is significantly less effective in NOD/LtSz-scid mice than in CB.17 scid mice

Groups of 8 to ten SCID (CB.17 scid/scid) or NOD/SCID (NOD/LtSz- scid/scid) mice were injected i.v. with two million human HSB-2 T-ALL cells on day 1 (SCID-HSB-2 and NOD/SCID-HSB-2 mice) and treated later with 3 i.v. 10 μg doses of the anti-CD7 antibody HB2 on days 7, 9 and 11 or with a single 10 μg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Flavell, D J, Warnes, S L, Noss, A L, Flavell, S U
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2000
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363443/ https://www.ncbi.nlm.nih.gov/pubmed/11104577 http://dx.doi.org/10.1054/bjoc.2000.1565

Ejemplares similares

Successful Establishment of an Orthotopic Hepatoblastoma In Vivo Model in NOD/LtSz-scid IL2Rγnull Mice
por: Ellerkamp, Verena, et al.
Publicado: (2011)

Higher susceptibility of NOD/LtSz-scid Il2rg(−/−) NSG mice to xenotransplanted lung cancer cell lines
por: Kanaji, Nobuhiro, et al.
Publicado: (2014)

Comparison of biological features between severely immuno-deficient NOD/Shi-scid Il2rg(null) and NOD/LtSz-scid Il2rg(null) mice
por: Nagatani, Mariko, et al.
Publicado: (2019)

Therapy of human T-cell acute lymphoblastic leukaemia with a combination of anti-CD7 and anti-CD38-SAPORIN immunotoxins is significantly better than therapy with each individual immunotoxin
por: Flavell, D J, et al.
Publicado: (2001)

The TLR3 Agonist Poly Inosinic:Cytidylic Acid Significantly Augments the Therapeutic Activity of an Anti-CD7 Immunotoxin for Human T-Cell Leukaemia
por: Flavell, David J., et al.
Publicado: (2019)

Comparison of the potency and therapeutic efficacy of the anti-CD7 immunotoxin HB2-saporin constructed with one or two saporin moieties per immunotoxin molecule.
por: Flavell, D. J., et al.
Publicado: (1997)

Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain(null) Mice
por: Cai, Shanbao, et al.
Publicado: (2011)

Effectiveness of HB2 (anti-CD7)--saporin immunotoxin in an in vivo model of human T-cell leukaemia developed in severe combined immunodeficient mice.
por: Morland, B. J., et al.
Publicado: (1994)

Reevaluation of NOD/SCID Mice as NK Cell-Deficient Models
por: Miao, Miao, et al.
Publicado: (2021)

Spiny mice (Acomys) cells fail to engraft in NOD scid gamma
por: Gaire, Janak, et al.
Publicado: (2023)

In vivo Effects of a Histone Deacetylase Inhibitor, FK228, on Human Acute Promyelocytic Leukemia in NOD/Shi‐scid/scid Mice
por: Kosugi, Hiroshi, et al.
Publicado: (2001)

Differential Post-Surgical Metastasis and Survival in SCID, NOD-SCID and NOD-SCID-IL-2Rγ(null) Mice with Parental and Subline Variants of Human Breast Cancer: Implications for Host Defense Mechanisms Regulating Metastasis
por: Milsom, Chloe C., et al.
Publicado: (2013)

Analysis of the CD1 Antigen Presenting System in Humanized SCID Mice
por: Lockridge, Jennifer L., et al.
Publicado: (2011)

Suppression of human breast tumors in NOD/SCID mice by CD44 shRNA gene therapy combined with doxorubicin treatment
por: Van Pham, Phuc, et al.
Publicado: (2012)

Rapid engraftment of human ALL in NOD/SCID mice involves deficient apoptosis signaling
por: Queudeville, M, et al.
Publicado: (2012)

Data in support of the bone analysis of NOD–SCID mice treated with zoledronic acid and prednisolone
por: Hori, Naoko, et al.
Publicado: (2016)

NOD Scid Gamma Mice Are Permissive to Allogeneic HSC Transplantation without Prior Conditioning
por: Verbiest, Tom, et al.
Publicado: (2016)

Human Umbilical Cord Blood-Derived CD34(+) Cells Reverse Osteoporosis in NOD/SCID Mice by Altering Osteoblastic and Osteoclastic Activities
por: Aggarwal, Reeva, et al.
Publicado: (2012)

Failure of Effector Function of Human CD8(+) T Cells in NOD/SCID/JAK3(−/−) Immunodeficient Mice Transplanted with Human CD34(+) Hematopoietic Stem Cells
por: Sato, Yoshinori, et al.
Publicado: (2010)

Preclinical studies with the anti-CD19-saporin immunotoxin BU12-SAPORIN for the treatment of human-B-cell tumours.
por: Flavell, D. J., et al.
Publicado: (1995)

Efficient derivation of embryonic stem cells from NOD-scid Il2rg(−/−) mice
por: Liu, Kang, et al.
Publicado: (2015)

Lymphoid reconstitution of the human fetal thymus in SCID mice with CD34+ precursor cells
Publicado: (1991)

Generation of Pediatric Leukemia Xenograft Models in NSG-B2m Mice: Comparison with NOD/SCID Mice
por: Gopalakrishnapillai, Anilkumar, et al.
Publicado: (2016)

Nanofiber-expanded human umbilical cord blood–derived CD34(+) cell therapy accelerates cutaneous wound closure in NOD/SCID mice
por: Kanji, Suman, et al.
Publicado: (2014)

FcγRII (CD32) modulates antibody clearance in NOD SCID mice leading to impaired antibody-mediated tumor cell deletion
por: Oldham, Robert J, et al.
Publicado: (2020)

Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras
Publicado: (1994)

Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice
por: Matsuda, Masashi, et al.
Publicado: (2019)

Acceleration of Bone Repair in NOD/SCID Mice by Human Monoosteophils, Novel LL-37-Activated Monocytes
por: Zhang, Zhifang, et al.
Publicado: (2013)

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγ(c)(null) Mice
por: Rapp, Anna E., et al.
Publicado: (2016)

Efficient derivation of extended pluripotent stem cells from NOD-scid Il2rg(−/−) mice
por: Du, Yaqin, et al.
Publicado: (2018)

Long Term Amperometric Recordings in the Brain Extracellular Fluid of Freely Moving Immunocompromised NOD SCID Mice
por: Reid, Caroline H., et al.
Publicado: (2017)

Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice
por: Was, Halina, et al.
Publicado: (2016)

Lack of tumorigenesis and protumorigenic activity of human umbilical cord mesenchymal stem cells in NOD SCID mice
por: He, Jie, et al.
Publicado: (2022)

Gene therapy of destructive arthritis in SCID mice
por: Sack, U, et al.
Publicado: (2003)

Co-transplantation of Human Mesenchymal Stem Cells Promotes Human CD34+ Cells Engraftment in a Dose-dependent Fashion in NOD/SCID Mice
por: Park, Seong-Kyu, et al.
Publicado: (2007)

A radiolabeled antibody targeting CD123(+) leukemia stem cells – initial radioimmunotherapy studies in NOD/SCID mice engrafted with primary human AML
por: Leyton, Jeffrey V., et al.
Publicado: (2015)

Effectiveness of combinations of bispecific antibodies for delivering saporin to human acute T-cell lymphoblastic leukaemia cell lines via CD7 and CD38 as cellular target molecules.
por: Flavell, D. J., et al.
Publicado: (1992)

Reference genomes for BALB/c Nude and NOD/SCID mouse models
por: Schmid-Siegert, Emanuel, et al.
Publicado: (2023)

Genetics of SCID
por: Cossu, Fausto
Publicado: (2010)

Expansion of Activated Memory CD4(+) T Cells Affects Infectivity of CCR5-Tropic HIV-1 in Humanized NOD/SCID/JAK3(null) Mice
por: Terahara, Kazutaka, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_d10hqqsrm020hj97vi38tne3ih