Definition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases

Malignant melanoma (MM) is thought to arise by sequential accumulation of genetic alterations in normal melanocytes. Previous cytogenetic and molecular studies indicated the 9p21 as the chromosomal region involved in MM pathogenesis. In addition to the CDKN genes (p16/CDKN2A, p15/CDKN2B and p19(ARF)...

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Detalles Bibliográficos
Autores principales: Palmieri, G, Cossu, A, Ascierto, P A, Botti, G, Strazzullo, M, Lissia, A, Colombino, M, Casula, M, Floris, C, Tanda, F, Pirastu, M, Castello, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363459/
https://www.ncbi.nlm.nih.gov/pubmed/11104570
http://dx.doi.org/10.1054/bjoc.2000.1513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363459/
https://www.ncbi.nlm.nih.gov/pubmed/11104570
http://dx.doi.org/10.1054/bjoc.2000.1513

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