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AQ4N: a new approach to hypoxia-activated cancer chemotherapy
Preclinical studies demonstrate that in vivo AQ4N enhances the anti-tumour effects of radiation and chemotherapeutic agents with a dose-modifying factor of approximately 2.0. With careful scheduling no, or very little, additional normal tissue toxicity should be observed. AQ4N is a bioreductive prod...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2000
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363465/ https://www.ncbi.nlm.nih.gov/pubmed/11104551 http://dx.doi.org/10.1054/bjoc.2000.1564 |