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Mechanisms of acquired resistance to 2-(4-aminophenyl)benzothiazole (CJM 126, NSC 34445)

2-(4-aminophenyl)benzothiazole (CJM 126) elicits potent growth inhibition in human-derived breast carcinoma cell lines, including oestrogen receptor-positive (ER+) MCF-7(wt)cells. Analogues substituted in the 3′ position with I (DF 129), CH (3)(DF 203), or CI (DF 229) possess an extended profile of...

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Detalles Bibliográficos
Autores principales: Bradshaw, T D, Chua, M-S, Orr, S, Matthews, C S, Stevens, M F G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363474/
https://www.ncbi.nlm.nih.gov/pubmed/10901382
http://dx.doi.org/10.1054/bjoc.2000.1231