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Caspase-3-like activity determines the type of cell death following ionizing radiation in MOLT-4 human leukaemia cells

Caspases, a family of cysteine proteases, play a central role in the pathways leading to apoptosis. Recently, it has been reported that a broad spectrum inhibitor of caspases, the tripeptide Z-VAD-fmk, induced a switch from apoptosis to necrosis in dexamethasone-treated B lymphocytes and thymocytes....

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Detalles Bibliográficos
Autores principales: Coelho, D, Holl, V, Weltin, D, Lacornerie, T, Magnenet, P, Dufour, P, Bischoff, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363500/
https://www.ncbi.nlm.nih.gov/pubmed/10944606
http://dx.doi.org/10.1054/bjoc.2000.1322