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Allelic losses in carcinoma in situ and testicular germ cell tumours of adolescents and adults: evidence suggestive of the linear progression model

Testicular germ cell tumours (TGCTs) may arise through a process of multi-step carcinogenesis, and loss of heterozygosity (LOH) at specific loci is likely to be an important early event, although this has not been studied in detail. In order to explore the pathogenetic relationships among TGCTs, we...

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Detalles Bibliográficos
Autores principales: Faulkner, S W, Leigh, D A, Oosterhuis, J W, Roelofs, H, Looijenga, L H J, Friedlander, M L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363524/
https://www.ncbi.nlm.nih.gov/pubmed/10952776
http://dx.doi.org/10.1054/bjoc.2000.1334