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Determinants of anti-vascular action by combretastatin A-4 phosphate: role of nitric oxide

The anti-vascular action of the tubulin binding agent combretastatin A-4 phosphate (CA-4-P) has been quantified in two types of murine tumour, the breast adenocarcinoma CaNT and the round cell sarcoma SaS. The functional vascular volume, assessed using a fluorescent carbocyanine dye, was significant...

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Detalles Bibliográficos
Autores principales: Parkins, C S, Holder, A L, Hill, S A, Chaplin, D J, Tozer, G M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363526/
https://www.ncbi.nlm.nih.gov/pubmed/10952787
http://dx.doi.org/10.1054/bjoc.2000.1361