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Single amino acid (arginine) deprivation: rapid and selective death of cultured transformed and malignant cells
The effects of arginine deprivation (–Arg) has been examined in 26 cell lines. Less than 10% of those with transformed or malignant phenotype survived for > 5 days, and many died more rapidly, notably leukaemic cells. Bivariate flow cytometry confirmed that vulnerable cell lines failed to move ou...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2000
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363527/ https://www.ncbi.nlm.nih.gov/pubmed/10952786 http://dx.doi.org/10.1054/bjoc.2000.1353 |