Retinoblastoma protein-initiated cellular growth arrest overcomes the ability of cotransfected wild-type p53 to induce apoptosis

The retinoblastoma gene, RB, participates in the regulation of the G1/S-phase transition and in p53-mediated apoptosis. We have previously reported that stably transfected RB functions as a growth and tumour suppressor in HTB9 human bladder carcinoma cells, which carry a mutation of the p53 gene at...

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Detalles Bibliográficos
Autores principales: Shinohara, H, Zhou, J, Yoshikawa, K, Yazumi, S, Ko, K, Yamaoka, Y, Mizukami, T, Yoshida, T, Akinaga, S, Tamaoki, T, Motoda, H, Benedict, W F, Takahashi, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363552/
https://www.ncbi.nlm.nih.gov/pubmed/10993652
http://dx.doi.org/10.1054/bjoc.2000.1411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363552/
https://www.ncbi.nlm.nih.gov/pubmed/10993652
http://dx.doi.org/10.1054/bjoc.2000.1411

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