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Combined RAF1 protein expression and p53 mutational status provides a strong predictor of cellular radiosensitivity
The tumour suppressor gene, p53, and genes coding for positive signal transduction factors can influence transit through cell-cycle checkpoints and modulate radiosensitivity. Here we examine the effects of RAF1 protein on the rate of exit from a G2/M block induced by γ-irradiation in relation to int...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2000
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363568/ https://www.ncbi.nlm.nih.gov/pubmed/10993658 http://dx.doi.org/10.1054/bjoc.2000.1409 |