A transgenic mouse model for tumour immunotherapy: induction of an anti-idiotype response to human MUC1

MUC1 is a membrane bound, polymorphic epithelial mucin expressed at the luminal surface of glandular epithelium. It is highly expressed in an underglycosylated form on carcinomas and metastatic lesions and is, therefore, a potential target for immunotherapy of cancer. The monoclonal antibody HMFG1 b...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilkinson, R W, Ross, E L, Lee-MacAry, A E, Laylor, R, Burchell, J, Taylor-Papadimitriou, J, Snary, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363579/
https://www.ncbi.nlm.nih.gov/pubmed/11027434
http://dx.doi.org/10.1054/bjoc.2000.1431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363579/
https://www.ncbi.nlm.nih.gov/pubmed/11027434
http://dx.doi.org/10.1054/bjoc.2000.1431

Ejemplares similares