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Overexpression of melanoma inhibitory activity (MIA) enhances extravasation and metastasis of A-mel 3 melanoma cells in vivo

The secreted MIA protein is strongly expressed by advanced primary and metastatic melanomas but not in normal melanocytes. Previous studies have shown that MIA serum levels correlate with clinical tumour progression in melanoma patients. To provide direct evidence that MIA plays a role in metastasis...

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Detalles Bibliográficos
Autores principales: Guba, M, Bosserhoff, A-K, Steinbauer, M, Abels, C, Anthuber, M, Buettner, R, Jauch, K-W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363599/
https://www.ncbi.nlm.nih.gov/pubmed/11027436
http://dx.doi.org/10.1054/bjoc.2000.1424