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Selective cancer cell killing by α-tocopheryl succinate

We report that α-tocopheryl succinate, a vitamin E analogue with pro-apoptotic properties, selectively kills cells with a malignant or transformed phenotype, i.e. multiple haematopoietic and carcinoma cell lines, while being non-toxic to normal, i.e. primary and non-transformed cells. These findings...

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Detalles Bibliográficos
Autores principales: Neuzil, J, Weber, T, Gellert, N, Weber, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363620/
https://www.ncbi.nlm.nih.gov/pubmed/11139318
http://dx.doi.org/10.1054/bjoc.2000.1559