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The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation

Proteolysis mediated by matrix metalloproteinases (MMPs) and serine proteinases is associated with cancer invasion and metastasis. Activation of latent proMMPs, and especially the proforms of the type IV collagen degrading gelatinases A and B (proMMP-2 and proMMP-9), is thought to be a critical step...

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Detalles Bibliográficos
Autores principales: Paju, A, Sorsa, T, Tervahartiala, T, Koivunen, E, Haglund, C, Leminen, A, Wahlström, T, Salo, T, Stenman, U-H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363633/
https://www.ncbi.nlm.nih.gov/pubmed/11355948
http://dx.doi.org/10.1054/bjoc.2001.1806