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The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation
Proteolysis mediated by matrix metalloproteinases (MMPs) and serine proteinases is associated with cancer invasion and metastasis. Activation of latent proMMPs, and especially the proforms of the type IV collagen degrading gelatinases A and B (proMMP-2 and proMMP-9), is thought to be a critical step...
Autores principales: | Paju, A, Sorsa, T, Tervahartiala, T, Koivunen, E, Haglund, C, Leminen, A, Wahlström, T, Salo, T, Stenman, U-H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363633/ https://www.ncbi.nlm.nih.gov/pubmed/11355948 http://dx.doi.org/10.1054/bjoc.2001.1806 |
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