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Loss of heterozygosity in the Hodgkin-Reed Sternberg cell line L1236
Hodgkin-Reed Sternberg cells are derived from germinal centre B-cells in most cases. Somatic mutations affecting their rearranged immunoglobulin genes were detected, rendering potential functional rearrangements non-functional. Under physiological conditions such cells would be designated to undergo...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363750/ https://www.ncbi.nlm.nih.gov/pubmed/11161403 http://dx.doi.org/10.1054/bjoc.2000.1593 |