Therapy of human T-cell acute lymphoblastic leukaemia with a combination of anti-CD7 and anti-CD38-SAPORIN immunotoxins is significantly better than therapy with each individual immunotoxin

Severe combined immunodeficient (SCID) mice injected i.v. with the human T-ALL cell line CCRF CEM (SCID-CEM mice) develop within 50 days life-threatening multi-organ growth of leukaemia cells. The development of leukaemia in SCID-CEM mice treated with three 10 μg i.v. doses of the anti-CD7 immunotox...

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Detalles Bibliográficos
Autores principales: Flavell, D J, Boehm, D A, Noss, A, Warnes, S L, Flavell, S U
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363766/
https://www.ncbi.nlm.nih.gov/pubmed/11207056
http://dx.doi.org/10.1054/bjoc.2000.1633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363766/
https://www.ncbi.nlm.nih.gov/pubmed/11207056
http://dx.doi.org/10.1054/bjoc.2000.1633

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