Telomerase activation cooperates with inactivation of p16 in early head and neck tumorigenesis

Alteration of the p16/pRb pathway may cooperate with telomerase activation during cellular immortalization and tumour progression. We studied p16 expression status by immunohistochemistry and telomerase activity using the TRAP assay in 21 premalignant lesions of the head and neck epithelium as well...

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Detalles Bibliográficos
Autores principales: Soria, J C, Morat, L, Commo, F, Dabit, D, Perie, S, Sabatier, L, Fouret, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363771/
https://www.ncbi.nlm.nih.gov/pubmed/11207046
http://dx.doi.org/10.1054/bjoc.2000.1647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363771/
https://www.ncbi.nlm.nih.gov/pubmed/11207046
http://dx.doi.org/10.1054/bjoc.2000.1647

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