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The rate of the 6174delT founder Jewish mutation in BRCA2 in patients with non-colonic gastrointestinal tract tumours in Israel

Inherited predisposition occurs in 5–10% of all gastrointestinal (GI) cancer patients, but with the exception of colorectal cancer (CRC), the genes involved in conferring genetic susceptibility remain largely unknown. Indirect evidence indicates that germline mutations in BRCA2 might be associated w...

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Detalles Bibliográficos
Autores principales: Figer, A, Irmin, L, Geva, R, Flex, D, Sulkes, J, Sulkes, A, Friedman, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363777/
https://www.ncbi.nlm.nih.gov/pubmed/11207041
http://dx.doi.org/10.1054/bjoc.2000.1605