A probability model for predicting BRCA1 and BRCA2 mutations in breast and breast-ovarian cancer families

Germline mutations in BRCA1 and BRCA2 genes predispose to hereditary breast and ovarian cancer. Our aim was to find associations between the clinical characteristics and positive mutation status in 148 breast cancer families in order to predict the probability of finding a BRCA mutation in a family....

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Detalles Bibliográficos
Autores principales: Vahteristo, P, Eerola, H, Tamminen, A, Blomqvist, C, Nevanlinna, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363799/
https://www.ncbi.nlm.nih.gov/pubmed/11237395
http://dx.doi.org/10.1054/bjoc.2000.1626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363799/
https://www.ncbi.nlm.nih.gov/pubmed/11237395
http://dx.doi.org/10.1054/bjoc.2000.1626

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