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A probability model for predicting BRCA1 and BRCA2 mutations in breast and breast-ovarian cancer families
Germline mutations in BRCA1 and BRCA2 genes predispose to hereditary breast and ovarian cancer. Our aim was to find associations between the clinical characteristics and positive mutation status in 148 breast cancer families in order to predict the probability of finding a BRCA mutation in a family....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363799/ https://www.ncbi.nlm.nih.gov/pubmed/11237395 http://dx.doi.org/10.1054/bjoc.2000.1626 |