Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML

Treatment failure in AML is often attributed to P-glycoprotein-associated multidrug resistance. However, the importance of increased DNA repair in resistant cells is becoming more apparent. In order to investigate the ability of the DNA repair inhibitor aphidicolin to modulate drug resistance, we co...

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Detalles Bibliográficos
Autores principales: Sargent, J M, Elgie, A W, Williamson, C J, Lewandowicz, G M, Taylor, C G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363802/
https://www.ncbi.nlm.nih.gov/pubmed/11237390
http://dx.doi.org/10.1054/bjoc.2000.1639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363802/
https://www.ncbi.nlm.nih.gov/pubmed/11237390
http://dx.doi.org/10.1054/bjoc.2000.1639

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