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Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML
Treatment failure in AML is often attributed to P-glycoprotein-associated multidrug resistance. However, the importance of increased DNA repair in resistant cells is becoming more apparent. In order to investigate the ability of the DNA repair inhibitor aphidicolin to modulate drug resistance, we co...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363802/ https://www.ncbi.nlm.nih.gov/pubmed/11237390 http://dx.doi.org/10.1054/bjoc.2000.1639 |