Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma

The RIZ (PRDM2) locus commonly undergoes loss of heterozygosity (LOH) and maps within the minimal deleted region on 1p36 in hepatocellular carcinoma (HCC). Although peptide-altering mutations of RIZ are rare in HCC, the RIZ1 product is commonly lost in HCC and has tumour suppressive activities. Here...

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Detalles Bibliográficos
Autores principales: Fang, W, Piao, Z, Buyse, I M, Simon, D, Sheu, J C, Perucho, M, Huang, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363805/
https://www.ncbi.nlm.nih.gov/pubmed/11259086
http://dx.doi.org/10.1054/bjoc.2000.1667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363805/
https://www.ncbi.nlm.nih.gov/pubmed/11259086
http://dx.doi.org/10.1054/bjoc.2000.1667

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