Downregulation and forced expression of EWS-Fli1 fusion gene results in changes in the expression of G (1) regulatory genes

Chromosomal translocation t(11;22)(q24:q12) is detected in approximately 90% of tumours of the Ewing family (ET). This translocation results in EWS-Fli1 gene fusion which produces a EWS-Fli1 fusion protein acting as an aberrant transcriptional activator. We previously reported that the inhibition of...

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Detalles Bibliográficos
Autores principales: Matsumoto, Y, Tanaka, K, Nakatani, F, Matsunobu, T, Matsuda, S, Iwamoto, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363806/
https://www.ncbi.nlm.nih.gov/pubmed/11259090
http://dx.doi.org/10.1054/bjoc.2000.1652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363806/
https://www.ncbi.nlm.nih.gov/pubmed/11259090
http://dx.doi.org/10.1054/bjoc.2000.1652

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