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Downregulation and forced expression of EWS-Fli1 fusion gene results in changes in the expression of G (1) regulatory genes
Chromosomal translocation t(11;22)(q24:q12) is detected in approximately 90% of tumours of the Ewing family (ET). This translocation results in EWS-Fli1 gene fusion which produces a EWS-Fli1 fusion protein acting as an aberrant transcriptional activator. We previously reported that the inhibition of...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363806/ https://www.ncbi.nlm.nih.gov/pubmed/11259090 http://dx.doi.org/10.1054/bjoc.2000.1652 |