Cargando…

Activation of Ca(2+)-dependent proteolysis in skeletal muscle and heart in cancer cachexia

Cachexia is a syndrome characterized by profound tissue wasting that frequently complicates malignancies. In a cancer cachexia model we have shown that protein depletion in the skeletal muscle, which is a prominent feature of the syndrome, is mostly due to enhanced proteolysis. There is consensus on...

Descripción completa

Detalles Bibliográficos
Autores principales: Costelli, P, Tullio, R De, Baccino, F M, Melloni, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363832/
https://www.ncbi.nlm.nih.gov/pubmed/11286475
http://dx.doi.org/10.1054/bjoc.2001.1696