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Activation of Ca(2+)-dependent proteolysis in skeletal muscle and heart in cancer cachexia
Cachexia is a syndrome characterized by profound tissue wasting that frequently complicates malignancies. In a cancer cachexia model we have shown that protein depletion in the skeletal muscle, which is a prominent feature of the syndrome, is mostly due to enhanced proteolysis. There is consensus on...
Autores principales: | Costelli, P, Tullio, R De, Baccino, F M, Melloni, E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363832/ https://www.ncbi.nlm.nih.gov/pubmed/11286475 http://dx.doi.org/10.1054/bjoc.2001.1696 |
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